KEGG   REACTION: R00237
Entry
R00237                      Reaction                               
Name
(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)
Definition
(3S)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate
Equation
C01011 <=> C00024 + C00022
Reaction class
RC00502  C00024_C01011
RC01205  C00022_C01011
Enzyme
4.1.3.25
Pathway
rn00660  C5-Branched dibasic acid metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.25
     R00237  (3S)-Citramalyl-CoA <=> Acetyl-CoA + Pyruvate
Overall reaction [br08210.html]
 Carbon fixation
  R00237
Orthology
K08691  malyl-CoA/(S)-citramalyl-CoA lyase [EC:4.1.3.24 4.1.3.25]
K18292  (S)-citramalyl-CoA lyase [EC:4.1.3.25]
Reference
1  [PMID:24657929]
  Authors
Sasikaran J, Ziemski M, Zadora PK, Fleig A, Berg IA
  Title
Bacterial itaconate degradation promotes pathogenicity.
  Journal
Nat Chem Biol 10:371-7 (2014)
DOI:10.1038/nchembio.1482
Other DBs
RHEA: 22615

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (1062)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (1060)   
All databases (1080)   

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